Melissa J. Armstrong, M.D., MSc, FAAN

Melissa J. Armstrong, MD
Melissa J. Armstrong, MD

Associate Professor, Department of Neurology
Director, Mangurian Clinical-Research Center for Lewy Body and Parkinson’s Disease Dementia


Norman Fixel Institute for Neurological Diseases at UF Health

3009 SW Williston Road

Gainesville, FL 32608

Phone (352) 294-5400
Fax 352-627-4295

Dr. Melissa J. Armstrong, MD, MSc is the Director of the Mangurian Clinical-Research Center for Lewy Body and Parkinson’s Disease Dementia at the University of Florida. She joined the UF Department of Neurology and the Center for Movement Disorders and Neurorestoration in 2015.

Dr. Armstrong graduated from Illinois Wesleyan University in 1995 with a major in chemistry and a minor in philosophy. She completed medical school at the Stritch School of Medicine (Loyola University Chicago), where she subsequently completed a preliminary residency year in internal medicine and her neurology residency. During her neurology residency she was recognized with awards for her clinical neurology skills and her residency research projects. Following her residency, she worked as a general neurologist at Loyola University Medical Center for a year before pursuing fellowship training in movement disorders. Dr. Armstrong was a clinical and research fellow at the highly respected Morton & Gloria Shulman Movement Disorders Centre in Toronto, Ontario (Canada) from 2008 through 2011 where she was an Edmond J. Safra Fellow in Movement Disorders. She also completed an MSc in clinical epidemiology and health care research at the University of Toronto Institute for Health Policy Management and Evaluation. Dr. Armstrong worked as an assistant professor in the Division of Movement Disorders at the University of Maryland from 2012 until moving to the University of Florida in 2015. During this time, she co-authored the book, “Parkinson’s Disease: Improving Patient Care” (Oxford American Neurology Library 2014). She was also recognized as part of the American Academy of Neurology’s Emerging Leaders Forum (2013-2014). In addition to her work in the field of movement disorders, she serves as an evidence-based medicine methodology consultant for the American Academy of Neurology, working on their clinical practice guideline development program.

Dr. Armstrong’s research interests include two main foci. She has strong clinical interests in cognitive impairment (problems with memory and thinking) in the parkinsonian disorders including Parkinson’s disease, Lewy Body Dementia, and the atypical parkinsonisms. As part of this work, she is interested in ways to assess and treat cognitive impairment and in ways to improve quality of life for both patients with cognitive impairment and their carepartners/caregivers and families. Part of her research focuses on engaging patients and care partners/caregivers directly to understand the questions that are relevant to their daily lives. Dr. Armstrong also performs research on best practices for developing clinical practice guidelines in neurology. She currently has funding from the Agency for Healthcare Research and Quality (AHRQ) to examine the impact of engaging patients, caregivers, and patient advocates during guideline development.

Dr. Armstrong contributes to “The Neurologist Is In” blog on the Neurology Now website. Read those blog posts on their site.


Dr. Armstrong was visiting the University of Maryland and recorded this video about Shared Decision Making. This is what we mean when we say “the patient is the sun”.